溴代二苯酮与丙腈负离子的光诱导加成反应

PHOTOINDUCED ADDITION OF PROPIONITRILE CARBANION TO M-BROMO BENZOPHENONE

芳香卤代物芳环上的卤原子在光诱导或电引发下可通过自由基链式亲核取代反应(S_(RN)|)而被有机负离子所取代。 我们以3-溴苯基-苯基-甲酮为底物,在丙腈碳负离子存在下进行光照,结果芳酮环上的溴原子未发生 S_(RN)|取代,而是在羰基上发生了光诱导加成反应,生成了未见文献报道的新化合物1-苯基-1-(3-溴苯基)-2-氰基丙醇-1(I)

The Addition reaction of the carbonyl group of 3-bromo benzophenone occurred in the presence of propionitrile carbanion under irradiation, and a new compound, l-phenyl-1-(3-bromophenyl)-2-cyano-propanol-1, was obtained excluding the SRN|substitution reaction of meta-bromo.