自体颅骨深低温保存再值的研究和应用

APPLICATION OF AUTOPLASTY OF CRANIAL BONE AFTER CRYOPRESERVATION

目的：研究深低温保存自体颅骨再植术的效果。方法：对２７例行自体冷藏颅骨再植术患者作术前骨组织病理检查，术后定期（１～１２个月）随访临床情况和头颅Ｘ线检查。结果：骨组织病理检查显示骨陷窝内可见骨细胞，部分细胞轻度萎缩，无骨细胞死亡和细胞破坏。２６例切口一期愈合；２５例缺损修补区平整稳定，外型美观，满意率９２６％。Ｘ线检查１２个月后绝大部分骨缝消失，达骨性愈合。结论：深低温保存自体颅骨骨细胞成活力保留、再植术方法简单，手术并发症少，可达解剖愈合。

Objective: To evaluate the efficacy of autoplasy of cranial bone after cryopreservation Methods: Bone tissue was examined pathologically before transplating Clinic situation and cranial X-ray check were followed up after operation 1-12 months in 27patients experienced autoplasty of cranial bone being cryopreserved Results: Bone cells appeared in the pit and partial cells were shrunk pathologically One stage healing showed in 26 case Satisfactoriness of this method was 92 6%in 25 cases,in which local repair on original cranial defect was smooth and steady X-ray examination showed that linear fissure disappeared after 12 months in most of patients Conclusion: Bone cell viability of cranial explants after cryopreservation was reserved The clinical applicalion of autoplasty of cranial bone after cryopreservation have some advantages, with low operative complications, requiring simple tech, and reaching anatomically healing