住院强化治疗在地区结核病控制中的作用

Intensified chemotherapy in hospital for regional tuberculosis control

目的：比较门诊随诊与强化阶段住院治疗、巩固阶段转门诊随诊的两种方式在地区结核病控制中的作用。方法：对２７５例初治菌阳肺结核患者的临床症状缓解时间、胸部Ｘ线检查情况、完成疗程情况、复发率、３个月及完成疗程痰菌阴转率等进行分析对比。结果：住院强化治疗的痰菌阴转率明显提高（Ｐ＜０．０１），复发率差异无显著性（Ｐ＞０．０５），完成疗程情况明显改善（Ｐ＜０．０１）。结论：住院强化治疗疗效优于门诊随诊。

Objective:To compare the effects of intensified chemotherapy in out patient department(OPD) and in hospital for regional tuberculosis control.Methods:275 smear positive untreated cases of tuberculosis were studied for X ray film of chest,time of remission,rate of relapse and rate of conversion into smear negative at different time after treatment.Results:For patients treated in hospital the smear conversion rate was significantly increased( P < 0.01 ),the condition of patients was getting much better as compared with patients treated in OPD( P < 0.01 ),but the change in rate of relapse was not significant( P >0.05).Conclusions:The effect of intensified chemotherapy in hospital is better than that in OPD.