硬膜外阻滞硝普钠降压时对肺功能的影响

DELIBERATE HYPOTENSION WITH SOBIUM NITROPRUSSDE BURING EPIBURAL BLOCK FOR INFLUENCE OF PULMONARY FUNCTION

硬膜外阻滞采用硝普钠降压,是安全、可靠、调节方便的控制性降压方法,可减少硝普钠的用量。24例的经验指出,硬膜外阻滞下采用的硝普钠降压用量范围,对PaCO_2和VD/VT无显著影响;降压期间PaO_2的下降与Qs/Qt的升高与硝普钠单位时间的用量呈正相关,当硝普钠用量大于2μg/min时,PaO_2下降和Qs/Qt升高逐渐明显地出现显著性差别。为此,降压期间应提高吸入气的氧浓度。

In 24 cases deliberate hypotension were induced by sobium nitroprusside (SNP) dur-ing epibural block for influence of pulmonary function. Them, PaCO_2 anb Vd/Vt had no(?)significant change.While their PaO_2 were decreased ane O_s/Q_t were increased, all ofthese changes hab a befinite quantity relationship with the dose of SNP. The fe ature of this anesthesia is epibural dlock an enhance the action of SNP and greatly reduced the dose of SNP required. Among these 24 cases, 11 of them SNP 1.26 ug/Kg/min were enough, there were not obvious change in PaO_2 anb Q_s/Q_t.While the other 2.9 ug/Kg/min shown the dec reased PaO_2 anb increased Q_s/Q_t significantly. Special attention to raise the FiO_2 ther efore is suggested for the sufety sake technique.