甘肃省武威市成人幽门螺杆菌流行病学调查

Epidemiological study on status of Helicobacter pylori in adult in Wuwei city

目的:了解胃癌高发地区武威市成人幽门螺杆菌(Hp)的感染情况,并对Hp感染相关因素进行分析,为本地区防治Hp提供科学依据.方法:在武威市城乡居民中随机抽取797例成人开展Hp感染率及相关因素的横断面研究.采用标准化问卷收集研究对象的个人疾病史、家族疾病史、危险因素、保护因素等信息,采用酶联免疫吸附试验(ELISA)检测血清HpIgG抗体.结果:武威市成人Hp感染率为81.8%,且随着年龄的增加有增加的趋势.χ2检验分析结果提示,Hp感染可能与年龄、职业、文化水平、饮水来源等因素有关.多因素logistic回归分析提示,职业、饮水来源、饭前洗手与否以及家中有无胃癌或胃部疾病患者是Hp感染的危险因素.结论:武威市成人具有较高的Hp感染率,Hp感染可能存在日常生活接触传播和水源传播途径.

AIM： To determine sero-prevalence of and factors for helicobacter pylori （ Hp ） infection among residents aged larger than 18 years, Wuwei city. METHODS： A Cross-sectional survey was conducted among 797 randomly selected residents aged larger than 18 years from villages and town of Wuwei city. Questionnaire was administered to collected medical and risk behavioral information . Venous blood was collected for Hp antibody testing. RESULTS： Hp prevalence rates were 81.8% , and increased with age. Prevalence of lip infection is associated with aged, occupation and drinking water source etc. According to multivariate analysis, variables such as occupation, drinking water source, before meal to wash hands and gastric cancer or gastrosis patient in family are most strongly associated with prevalence of H. priori in adult. CONCLUSION： Hp infective rate was high in Wuwei city. The data support the daily life of contact and water resources transmission as the primary transmission pathways of H. priori.