胃多发癌的外科治疗及预后分析

Therapeutic options and prognosis of multifocal gastric carcinomas

目的探讨胃多发癌的临床病理特征、外科治疗方法及其预后。方法对1999年1月—2007年12月手术治疗的22例胃多发癌患者的临床资料进行回顾性分析，并结合文献进行生存分析。结果胃多发癌多见高龄男性，早期胃癌占28．9％，共施行根治性切除18例，姑息性切除4例，1、3、5年生存率分别为80．9％、52．4％、28．6％。结论胃癌患者应于术前及术中进行仔细检查，避免漏诊，经合理治疗胃多发癌的治疗效果与单发胃癌相似。

Objective To investigate the clinicopathological characteristics, therapeutic principles and prognosis of muhifocal gastric carcinomas. Methods The data of 22 patients with muhifocal gastric carcinomas surgically treated at our hospital from January 1999 to December 2007 were reviewed retrospectively. Results The muhifocal gastric carcinomas occurred frequently in the elderly men; the percentage of early stage gastric carcinoma was 28.9%. Eighteen patients received radical resection while 4 patients palliative resection. The 1, 3 and 5-year survival rates were 80. 9%, 52. 4% and 28. 6% respectively. Conclusions A thorough gastric examination should be made before and during resection so as to avoid a missing diagnosis. The postoperative survival in patients with multifocal gastric carcinomas is similar to those with a solitary lesion.