^(99m)Tc—EHIDA肝胆显像对肝门局部冷冻损伤的评价

Evaluation of (99m)~Tc-EHIDA hepatobiliary imaging for regional porta hepatis cryosurgery

对实验动物小猪第一肝门冷冻后1、2周及对照组进行SPECT肝胆动态显像。结果发现肝门冷冻区放射性分布稀疏或缺损样改变，而肠道出现放射性的时间明显延长，与对照组比较差异显著。结果提示，胆道系统受损，对肝门区进行直接深低温冷冻治疗时，应该对胆道系统加以保护，避免产生严重并发症。

99mTc-EHIDA radionuclide hepatobiliary imaging was performed to evaluate the hepatobiliary functional changes one to two weeks after cryosurgery in porta hepatis of porcine. The imaging shown that the radioactivity of cryosurgical hepatic region was decreased or absent. The time of appearence of radioactivity in intestines was significantly prolonged, and was statistically significant as compared with control group. The binary tract system was damaged. It was suggested that the prefect protection of binary system should be accomplished in the cryosurgery of porta hepatis to avoid severe complications.