糖尿病对血液透析患者长期生存率及并发症的影响

The impact of diabetes on long-term survival rate and complication in uremic patients during hemodialysis

目的探讨糖尿病对维持性血液透析患者的长期生存率及并发症的影响。方法选取1999—2004年维持性血液透析患者100例,根据是否合并糖尿病分为两组:糖尿病组和对照组。统计1、3、5年死亡率并分析死因,观察患者血透过程中低血糖、病程中心血管并发症、严重感染和脑血管意外发生率。结果合并糖尿病的患者3、5年死亡率较高(P<0.05),感染死亡率较高,心脑血管并发症,低血糖和感染发生率较高,差异有统计学意义(P<0.05)。结论合并糖尿病的维持性血透患者长期生存率较低,并发症发生率较高。

Objective To investigate the impact of diabetes on long-term survival rate and complications in uremic patients during hemodialysis maintenance. Methods A total of 100 patients on hemodialysis maintenance at our hospital were surveyed from 1999 to 2004. All subjects were categorized into two groups according to their diabetic complications：the diabetic group and the control group. One-, three-, and five-year survival rates were evaluated and the death causes were analyzed in both groups. Cardiovascular and cerebrovascular diseases, severe infections, hypoglycemia were found as main complications. Results There were significant differences in the three-year and five-year survival rates between two groups （ P 〈 0.05 ）, with more deaths from infections in the diabetic group. The incidence rates of cardiovascular and cerebrovascular diseases, severe infections, and hypoproteinemia were higher in diabetic group （ P 〈 0.05 ）. Conclusion During hemodialysis maintenance, lower survival rate and higher incidence of complications are found in diabetic patients.