糖尿病足54例治疗体会

Curative Experience of Fifty-four Diabetic Foot Patients

目的观察川芎嗪治疗糖尿病足的临床效果。方法将54例糖尿病足患者随机分为2组,观察组患者静脉滴注川芎嗪注射液,对照组患者静脉滴注复方丹参注射液,均治疗4周,然后比较2组疗效。结果观察组总有效率为70.4%,对照组为48.1%;起效时间观察组为(6±1.2)d,对照组为(10±1.0)d,差异均有统计学意义(P<0.05)。在治疗过程中2组均未出现不良反应。结论川芎嗪治疗糖尿病足安全有效,其疗效明显优于复方丹参注射液。

Objective To observe the clinical effect of curing the diabetic foot with tetramethylpyra-zine（TMP）. Method Fifty-four patients are randomly divided into two groups, one as the clinical observation group,receiving injection of the tetramethylpyra-zine injection with intravenous drip, and the other as clinical comparison group, receiving injection of the Fufang Danshen injection with intravenous drip. Both groups are cured for four weeks, then the curative effect of them are compared. Results Effectivity rate in the clinical observation group was 70.4%,whilein the clinical comparison group 48.1%. Operative time（6±1. 2）d vs （10±1. 0）d. The differences were significant（P〈0.05）. There were no adverse reaction in two groups. Conclusion It is safe and available to cure the diabetic foot with the tetramethylpyra-zine injection and its curative effect is better than the Fufang Danshen injection.