摘要
通过虫白蜡还原法制备高级烷醇混合物探索研究,得到虫白蜡制备高级烷醇混合物的工艺优化条件:10g虫白蜡还原制备高级烷醇,氢化铝锂用量0.7g,四氢呋喃溶剂用量70mL,在65℃、常压和超声波作用条件下,进行还原反应5h后,用水煮沸洗涤2-3次,过滤,滤饼烘干,虫白蜡转化率可达到95%-98%。用有机溶剂重结晶高级烷醇混合物后,用气相色谱测定组成为二十六烷醇56%、二十八烷醇32%、二十四烷醇5.2%、三十烷醇4.0%、二十五烷醇1.5%、二十七烷醇0.9%。
Policosanol was prepared from insect wax reduced by LiAlH4. The optimized condition is: 0.7 g LiAlH4 and 70 mL tetrahydrofuran with 10 g wax, reaction temperature 65℃, atmospheric pressure and ultrasonic condition for 5 h for reducing reaction. The product was washed with boiling water for 2-3 times, then filtered and dried to obtain policosanol (crude) of 95 %-98 % yield. After recrystallizing the crude policosanol from organic solvent for 3 times and dried, the obtained policosanol has the composition of hexacosanol 56 %, octacosanol 32 %, tetracosanol 5.2 %, triacontanol 4.0 %, pentacosanol 1.5 %, heptacosanol 0.9 % by GC analysis.
出处
《林产化学与工业》
EI
CAS
CSCD
北大核心
2009年第5期6-10,共5页
Chemistry and Industry of Forest Products
基金
"十一五"国家科技支撑计划资助(2006BAD06B07)
国家林业局重点项目资助(2006-54)
关键词
虫白蜡
还原剂
高级烷醇
还原反应
氢化铝锂
insect wax
reducing agent
policosanol
reduction reaction
lithium aluminium tetrahydride ( LiAlH4 )