退黄洗液辅助治疗新生儿黄疸的疗效观察

Curative Effects of Chinese Herbal Lotion(Tui Huang Xi Ye) as Adjunctive Therapy on Neonatal Jaundice

目的探讨新生儿退黄洗液泡浴辅助治疗新生儿黄疸的疗效。方法120例病理性黄疸的新生儿按随机数字表法分为对照细及观察组各60例，两组口服药相同，观察组辅以退黄洗液泡浴，各组治疗期间如病情加重达到光疗指标者给予光疗。结果在出生〈48h,48-71h、≥72h不同适龄黄疸患儿的治疗中，对照组中转光疗的病例33例，占55．0％，观察组4例，占6．7％，两组比较差异有统计学意义（x^2=32．862，P=0．000）；两组治疗前后血清三胆差值比较差异无统计学意义（P〉0．05）；去除光疗因素，对照组总胆红素、间接胆红素治疗后上升值高于观察组，两组比较差异有统计学意义（P〈0．05）。结论新生儿退黄洗剂泡浴辅助治疗新生儿黄疸可缓解病情，减少蓝光治疗。因用药简单方便和无毒副作用，适用于病情较轻的初生新生儿黄疸的选择性治疗和居家使用。

Objective To explore the curative effect of medicated bath with jaundice-abating Chinese Herbal Lotion （Tui Huang Xi Ye） as adjunctive therapy on the neonatal jaundice in the obstetrical department. Methods 120 cases of first born neonatal pathological jaundice divided randomly into two groups ,60 cases of experimental group undergone with oral taken medicine plus medicated bath, whereas the control group undergone oral taken medicine only. All the patients whose condition worsened in both groups were undergone a pbototherapy. Results During the different onset time （ 〈48 h,48-71 h,≥72 h） of neonatal jatmdice,there was 33 cases with the phototherapy in the control group（55.0% ）,4 cases in the observed group （6.7%）, the difference was significant （x^2 = 32. 862,P = 0. 000） ;but there was no significant difference between the serum bilirubin of the pretherapy and post-treatment of two groups （P 〉 0.05 ） ; removal of the cases with the phototherapy of the two groups,the increment of total bilirubin and indirect bihrubin after treament of the control group was significantly higher than that of the observation group,which was statistically significant（P 〈 0.05）. Conclusion Medicated bath with jaundice-abating Chinese Herbal Lotion as adjunctive therapy on the neonatal jaundice is suggested cure-effective and might decrease the using of phototherapy and cut the cost. It is suitable for those first bore neonatal jaundice neonates without high-risk factor and those out-patient department neonates.