血栓通治疗急性脑梗死的疗效及对血流动力学的影响

Therapeutic effect of xueshuantong for acute cerebral infarction and its influence on hemodynamics

目的观察血栓通治疗急性脑梗死的临床疗效及对血流动力学的影响。方法将105例急性脑梗死患者随机分为治疗组53例和对照组52例,分别给予血栓通和复方丹参注射液治疗。观察两组临床疗效,并在治疗前后进行经颅多普勒(TCD)测定。结果治疗组的显效率为50.9%,而对照组的显效率则为28.8%,两者比较有统计学意义(P<0.05);治疗组的总有效率为86.8%,显著优于对照组的61.5%(P<0.01)。在治疗后,治疗组TCD各参数均有明显改善(P<0.05和P<0.01),且与对照组比较有统计学意义(P<0.01)。结论血栓通治疗急性脑梗死安全、有效,能明显改善患者的血流动力学指标。

Objective To observe the clinical effect of xueshuantong in treatment of patients with acute cerebral infarction（ACI） and its influence on hemodynamics. Methods One hundred and five cases with ACI were di- vided randomly into treatment group and control group, receiving treatment of xueshuantong and fufang danshen injection respectively. The clinical efficacy were observed of two groups, and transcranial doppler（TCD） were examined before and after treatment. Results The improving rate of treatment group was significantly higher than that of control group（50. 9% vs 28. 8%, P 〈 0. 05 ）. The total effectiveness rate of treatment group was significandy higher than that of control group（86. 8% vs 61.5%, P 〈0.01 ）. Comparied with those before treatment, the indices of TCD in treatment group improved obviously after treatment（ P 〈 0.01 or P 〈 0. 05）, and had significant difference from control group （P 〈 0.01 ）. Conclusion Xueshuantong is effective and safe for ACI, and can obviously improve the indices of hemodynamics.