经皮冠状动脉介入治疗对冠心病合并心力衰竭患者疗效评价

Effect of percutaneous coronary interventions on heart function in patients with coronary heart disease and heart failure disease

目的观察经皮冠状动脉介入治疗对冠心病患者左心室收缩和舒张功能的疗效。方法选择72例冠心病合并心力衰竭的患者,行经皮冠状动脉介入治疗,术前、术后1周和术后6个月分别行心脏超声检查左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、左室短轴缩短率(FS)、左室射血分数(LVEF)、舒张早期血流峰值速度(E)、舒张晚期血流峰值速度(A)以及E峰和A峰比值(E/A),比较术前和术后患者心功能变化情况。结果通过行介入治疗后,支架植入术后冠心病合并心力衰竭患者心功能较前有了明显的好转,术后6个月LVEF、FS、LVESD、LVEDD、E、A和E/A与术前相比均有明显改善(P<0.05和0.01),术后一周LVEF和FS与术前相比有改善(P<0.05)。术后6个月与术后一周相比LVEF、FS、LVESD和LVEDD有明显改善(P<0.05)。结论经皮冠状动脉介入治疗能够明显改善冠心病合并心力衰竭患者的心功能。

Objective To investigate the effect on left ventricular systolic and diastolic function in patients with coronary heart disease（CHD） after percutaneous coronary interventions（PCI）.Methods 72 CHD patients with heart failure disease who underwent PCI were selected.Left ventricular end systolic diameter（LVESD）,Left ventricular end diastolic diameter（LVEDD）,Fraction shortening（FS）,Left ventricular ejection（LVEF）,E,A and E/A were measured with Doppler echocardiography before operation,one weeks and 6 months after operation.Results SAfter percutaneous coronary interventions,the systolic and diastolic function in CHD patients with heart failure were significantly improved.LVEF、FS、LVESD、LVEDD、E、A and E/A were significantly improved（P〈0.05,0.01） six months after operation compared with before operation.LVEF and FS were improved（P〈0.05） one week after operation compared with before operation.LVEF、FS、LVESD and LVEDD were improved（P〈0.05） six months after operation compared with one week after operation.Conclusion The systolic and diastolic function in CHD patients with heart failure were inproved after percutaneous coronary interventions.