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小儿门诊外科手术应用瑞芬太尼复合丙泊酚可行性 被引量:8

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摘要 目的观察瑞芬太尼复合丙泊酚静脉麻醉在小儿门诊外科手术中应用的可行性。方法选择外科择期手术2~5岁小儿60例,随机分为3组各20例,所有患儿术前均禁食4h,禁饮2h,入室前3组患儿均肌内注射阿托品0·02mg·kg-1、氯胺酮5mg·kg-1实施基础麻醉。I组为对照组,术中间断静脉注射1%氯胺酮0·5~1·0mg·kg-1;II组以瑞芬太尼0·1μg·kg-1·min-1持续泵注;III组以瑞芬太尼0·2μg·kg-1·min-1持续泵注;3组均复合丙泊酚3mg·kg-1·h-1泵注维持麻醉。所有患儿经面罩吸入纯氧3~5L·min-1,术中不用肌肉松弛药,维持自主呼吸或必要时手控辅助呼吸。从麻醉诱导开始到手术切皮之前(诱导期)未给予患者任何刺激,并保证此段时间>5min,以确保在切皮时患者体内有稳定的血药浓度。手术结束前5min停止泵注异丙酚和瑞芬太尼。监测心率,呼吸频率、节律、幅度、潮气量、PetCO2和SpO2等指征,记录切皮和术中有无肢动反应等麻醉过浅体征,记录停药后患儿麻醉恢复情况。结果Ⅱ组生命体征平稳,麻醉效果良好且麻醉恢复快。结论瑞芬太尼复合丙泊酚静脉麻醉应用于小儿门诊外科手术,具有安全、高效、苏醒迅速及后遗症少等特点,尤其是第Ⅱ组方法,在满足手术要求的同时,对患儿呼吸循环系统影响轻微,是一种较安全的麻醉方法。
出处 《医药导报》 CAS 2009年第11期1462-1463,共2页 Herald of Medicine
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