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Environmental Impacts on Spiking Properties in Hodgkin-Huxley Neuron with Direct Current Stimulus

Environmental Impacts on Spiking Properties in Hodgkin-Huxley Neuron with Direct Current Stimulus
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摘要 Based on the well accepted Hodgkin-Huxley neuron model, the neuronal intrinsic excitability is studied when the neuron is subject to varying environmental temperatures, the typical impact for its regulating ways. With computer simulation, it is found that altering environmental temperature can improve or inhibit the neuronal intrinsic excitability so as to influence the neuronal spiking properties. The impacts from environmental factors can be understood that,the neuronal spiking threshold is essentially influenced by the fluctuations in the environment. With the environmental temperature varying, burst spiking is realized for the neuronal membrane voltage because of the environment-dependent spiking threshold. This burst induced by changes in spiking threshold is different from that excited by input currents or other stimulus. Based on the well accepted Hodgkin-Huxley neuron model, the neuronal intrinsic excitability is studied when the neuron is subject to varying environmental temperatures, the typical impact for its regulating ways. With computer simulation, it is found that altering environmental temperature can improve or inhibit the neuronal intrinsic excitability so as to influence the neuronal spiking properties. The impacts from environmental factors can be understood that,the neuronal spiking threshold is essentially influenced by the fluctuations in the environment. With the environmental temperature varying, burst spiking is realized for the neuronal membrane voltage because of the environment-dependent spiking threshold. This burst induced by changes in spiking threshold is different from that excited by input currents or other stimulus.
出处 《Chinese Physics Letters》 SCIE CAS CSCD 2009年第11期239-241,共3页 中国物理快报(英文版)
基金 Supported by the National Natural Science Foundation of China under Grant Nos 10775038 and 10747123, and the Hebei Provincial Natural Science Foundation under Grant Nos A2007000001 and C2007000026. We would like to thank Professor Yizhong Zhuo for helpful discussion.
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  • 1Rabinovich M I, Varona P, Selverston A I and Abarbanel H D I 2006 Rev. Mod. Phys. 78 1213.
  • 2Feng J and Tuckwell H C 2003 Phys. Rev. Lett. 91 018101.
  • 3Makarov V A, Nekorkin V I and Velarde M G 2001 Phys. Rev. Lett. 86 003431.
  • 4Hodgkin A L and Katz B 1949 J. Physiol. 109 240.
  • 5Hermans M M P, Kortetcuas P, Jongsma H J and Rook M B 1995 Eur. J. Physiol. 431 138.
  • 6Prina-Mello A, Farrell E, Prendergast P J, Campbell V and Coey J M D 2005 Physica Scripta T118 205.
  • 7Hallett M 2007 Neuron 55 187.
  • 8Cao X and Oertel D 2005 J. Neurophysiol. 94 821.
  • 9Moore J W 1958 Fed. Proc. 17 113.
  • 10Zhao Y and Boulant J A 2005 J. Physiol. 564 245.

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