摘要
目的:了解我院药品不良反应(ADR)的发生情况及特点。方法:将我院2004~2008年收集的ADR报告560例,按患者性别、年龄、涉及药品种类、给药途径、临床表现等进行统计、分析。结果:在我院上报的ADR中,抗感染药引发的ADR占51.8%,中药制剂占10.7%;ADR类型以皮肤及其附件损伤最常见,占51.8%,无死亡病例报道。结论:临床应加强ADR监测工作,尤其要严格把握抗感染药及中成药的使用指征,减少ADR的发生。
OBJECTIVE: To probe into the status quo and characteristics of the adverse drug reactions (ADR) occurred in our hospital. METHODS: A total of 560 ADR cases collected in our hospital from 2004 to 2008 were analyzed statistically in respect of patients' age and sex, drug varieties, route of administration and clinical manifestation, etc. RESULTS: Of all the ADR cases reported in our hospital, 51.8% were induced by anti- infective drugs vs. 10.7% by traditional Chinese medicines; 51.8% manifested as lesions of skin and its appendants, but none of them died. CONCLUSION: Clinical importance should be attached to the monitoring of ADR, the indications of the anti - infective drugs and traditional Chinese medicines should be strictly followed in order to decrease the incidence of ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第32期2541-2543,共3页
China Pharmacy
关键词
药品不良反应
报告
监测
统计分析
Adverse drug reaction
Report
Monitoring
Statistical analysis