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麝香保心丸联合阿托伐他汀治疗不稳定型心绞痛疗效观察 被引量:7

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摘要 目的:探讨麝香保心丸联合阿托伐他汀治疗不稳定型心绞痛的临床疗效。方法:选择我院62例不稳定型心绞痛患者,随机分为治疗组和对照组,对照组在常规治疗基础上加用麝香保心丸,治疗组在对照组基础上加用阿托伐他汀,观察两组治疗前后心绞痛发作的频率、持续时间、发作间期,Holter24h缺血总时间、心电图T波及ST-T改变。结果:治疗组在疗效、症状改善方面均优于对照组。结论:麝香保心丸联合阿托伐他汀治疗不稳定型心绞痛疗效显著,值得临床借鉴。
作者 李香玉
出处 《中国医药导报》 CAS 2009年第32期39-39,42,共2页 China Medical Herald
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  • 1Marti'nez-Gonza'lez J, Raposo B, Rodriguez C, et al. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibition prevents endothelial NO synthase downregulation by atherogenie levels of native LDLs: balance between transcriptional and posttranscriptional regulation [J]. Arterioscler Thromb Vasc Biol, 2001,21: 804.
  • 2Feron O, Dessy C, Desager JP, et al. Hydroxy-methylglutarylcoenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance [J]. Circulation, 2001, 103:113-118.
  • 3Laufs U, Liao JK. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase [J]. J Biol Chem, 1998, 273:24266-24271.
  • 4Yamada M, Huang Z, Dalkara T, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by larginine after chronic statin treatment [J]. J Cereb Blood Flow Metab, 2000, 20; 709-717.
  • 5Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, et al. Effects of the 3-hydroxy-3-methylglutaryl - CoA reduetase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells [J]. J Clin Invest, 1998, 101 (12):2711-2719.
  • 6Rasmussen LM, Hansen PR, Nabipour MT, et al. Diverse effects of inhibition of 3 - hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM- 1 and E-selectin in endothelial cells [J]. Biochem J, 2001, 360: 363-370.
  • 7Herna'ndez-Presa MA, Ortego M, Tunon J, et al. Simvastatin reduces NF-kB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet [J]. Cardiovasc Res, 2003, 57: 168-177.
  • 8Ridker PM, Rifai N, Pfeffer MA, et al. Long term effects of pravastatin on plasma concentrations of C-reactive protein. The cholesterol and recurrent events (CARE) investigators [J ]. Circulation, 2000, 100: 230-235.
  • 9Kinlay S, Rifai N, Libby P, et al. Effect of atorvastatin on C-reactive protein in patients with acute coronary syndrome: a substudy of the MIRACL trial [J]. J Am Coll Cardiol, 2002, 39 (Suppl A):304A.
  • 10Plenge JK, Hernandez TL, Weil KM, et al. Simvastatin lowers C-reactive proten within 14 days:an effect independent of lowdensity lipoprotein cholesterol reduction [J]. Circulation, 2002, 106: 1447-1452.

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