放疗联合热疗治疗晚期食管癌的临床观察

目的观察放疗联合热疗对晚期食管癌的近期疗效,与单纯放疗作对比。方法外照射联合热疗(R+H)组40例,单纯外照射(RT)组40例。R+H组:常规放疗,每次2Gy/次,5次/周,总剂量66～70Gy/6.5～7周,热疗每周2次,功率800～1000W,每次加热1小时,共6～8次;RT组:常规放疗,每次2Gy/次,5次/周,总剂量66～70Gy/6.5～7周。结果R+H组近期疗效为90%,明显高于RT组的65%,两者比较前者明显升高,有统计学意义(P<0.05)。结论外照射联合热疗能提高食管癌的近期治疗效果。

Objective To evaluate and compare the short-term effectiveness in the treatment of advanced esophageal carcinoma treated by radiotherapy and hyperthermia.Methods Forty patients received radiotherapy with hyperthermia,forty paients received radiotherapy alone.In the R＋H group, radiotherapy DT 66-70Gy, hyperthermia（800-1000WOne hour）twice a week total 6-8 times.In the RT group, radiotherapy DT 66-70Gy. Results the short-term effectiveness in the treatment （CR＋PR） in the R＋H group is better than that of RT group significantly （P〈0.05）Conclusion Radiotherapy combined with hyperthermia in treatment of advanced esophageal cancer is moreeffective than radiotherapy alone.