消化系统器质性疾病患者抑郁焦虑现状及其影响因素的调查

Study on the Prevalence and Risk Factors of Depressive and Anxious Symptoms of Patients with Digestive Organic Diseases

目的了解消化系统器质性疾病患者抑郁/焦虑的患病率,并探讨导致抑郁/焦虑的影响因素。方法连续收集经确诊的消化系统器质性疾病患者434例,采用综合性医院焦虑抑郁量表进行心理测评,对数据进行多因素非条件Logistic回归分析。结果消化系统器质性疾病患者抑郁/焦虑的患病率为33.88%,其中患病率较高的疾病为胰腺炎、肿瘤、溃疡性结肠炎。高中以上学历为单纯抑郁、单纯焦虑、抑郁合并焦虑的保护性因素,OR值分别为0.302、0.333、0.284;年龄超过40岁为单纯抑郁、抑郁合并焦虑的危险因素,OR值分别为5.904、5.238;非体力劳动为单纯抑郁的危险因素,OR值为2.842;而性别与抑郁/焦虑无关。结论消化系统器质性疾病患者存在着较高的抑郁/焦虑患病率,而高中及以下学历、年龄超过40岁、非体力劳动可能为其危险因素。

Objective To explore the prevalence and possible risk factors of depressive/anxious symptoms of patients with digestive dis- eases. Methods Totally 454 eligible subjects with digestive diseases were recruited consecutively. Face-to-face interview and the Hospital Anxiety and Depression Scale （HADS） were employed to collect the clinical data. The non-condition logistic regression was performed to analyze the data. Results The prevalence rate of depressive/ anxious symptom was 33.9%, among which pancreatitis, cancer, and ulcerative colitis were the most common diseases. The senior high school above was a protective factor of depression,anxiety,depression and anxiety （OR was respectively 0.302,0.333,0.28d ）. Forty years or older was a risk factor of depression, anxiety and depression （OR was respectively 5.904,5.238 ）. Non-manual work was a risk factor of depression （OR is 2.842）. There was no correlation between the gender and depres- sion/anxiety. Conclusion There is a higher prevalence of depressive and anxious symptoms in patients with digestive organic diseases. Senior high school or lower, older than 40 years, and non-manual work are the risk factors for these symptoms.