聚维酮碘在预防550例剖宫产术后感染的应用

Application of povidone iodine in preventing infection after casarean section in 550 cases

目的探讨聚维酮碘(povidone iodine)预防高危感染因素的剖宫产术后切口及宫腔感染的作用。方法对550例具有高危感染因素的剖宫产患者应用聚维酮碘与甲硝唑组及对照组进行临床观察对比。结果术后病率及术后5d内低热持续天数,聚维酮碘组与甲硝唑组比较差异有统计学意义(P<0.05),与对照组相比差异有统计学意义(P<0.01)。术后5d内的平均体温变化聚维酮碘组与甲硝唑组相比差异有统计学意义(P<0.05),与对照组相比差异有统计学意义(P<0.01)。术后白细胞总数大于20×109/L者明显少于甲硝唑组及对照组。从腹部切口感染情况看,聚维酮碘组无感染率(96%)明显高于甲硝唑组(71.1%)和对照组(52.4%),差异有统计学意义(P<0.01)。结论聚维酮碘预防剖宫产术后感染是经济、方便、有效的较好措施,值得推广。

Objective To study the effect of povidone iodine in preventing incision and intrauterine infections after cesarean section with high inefctious risk. Methods The application of povidone iodine and metronidazole in 550 cases of cesarean section with high infectious risk in our hospital were investigated and compared with the control group. Results The postoperative infection rate and continuous days of low fever after 5d of operation had staistical significance between the povidone iodine group and metronidazole group（P〈0.05） and between the treatment groups and the control group（P〈0.0l）. The average change of body temperature within 5d after operation also had statistical significance between the povidone iodine group and rnetronidazole group（P〈0.05） and between the treatment groups and the control group（P〈0.01）. The patients with postoperative WBC counts 〉20 × 10^9/L in the povidone iodine group were less than those of the metronidazloe group and control group. The noninfection rate （96% ） of abdominal incision infection in the povidone iodine group was obviously higher than that （71.1% , 52.4% ） of the rnetronidazole group and the control group with statistical significance （P〈0. 01）. Conclusion Preventing infection after cesarean section by povidone iodine is economic, convenient and effective better measure being worth promoting.