野菊花黄酮类成分研究

Studies on Flavones from Flos Chrysanthemi Indici

目的：研究野菊的干燥头状花序中的化学成分。方法：用硅胶柱色谱法及Sephadex LH-20柱色谱法进行分离纯化，依据理化性质和光谱数据鉴定化合物结构。结果：从野菊花的80％乙醇提取物中分离得到了7个黄酮化合物，分别被鉴定为：木犀草素（1）、木犀草素-7-O-β-D-葡萄糖苷（2）、木犀草素-7-O-（6＂-O-乙酰基）-β-D-葡萄糖苷（3）、香叶木素（4）、香叶木素-7—O-β-D-葡萄糖苷（5）、异泽兰黄素（6）和芹菜素（7）。结论：化合物3～6为首次从野菊花中分离得到。

Objective： To study the chemical constituents of Flos Chrysanthemi Indici. Methods ： Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. Their structures were indentified by means of physicochemical and spectral data. Results： From the 80% ethanol extract of the material, seven compounds were isolated. Their structures were identified as luteolin （ 1 ）, luteolin-7-O-β-D-glucopyranoside （ 2 ）, luteolin-7-O- （ 6-O-acetyl ） -β-D-glucopyranoside （ 3 ）, diosmetin （4）, diosmetin-7-O-β-D-glucopyranoside （5）, eupatilin （ 6 ） and apigenin （7）, respectively. Conclusion ： Compounds 3 - 6 are isolated from Flos Chrysanthemi Indici for the first time.