后基因组时代方剂学研究的反思

Research on science of herbal formula in post-genome era

通过对目前方剂学基础研究的分析,指出还原分析方法不能成为学科研究的核心方向,微观指标变化不能取代宏观功能变化成为现代化的标准,真正的现代化是宏观和微观的相互印证、互相补充。方剂学的核心内容除了配伍规律和方证相关,应该注重治法的研究,研究方法应从传统方剂学的理论和临床实际出发,走方剂学理论原创的道路,方剂学的真正发展,在于方剂学的理论创新,而不应把方剂学变成开发中成药的工具,这有利于方剂学的长远发展。

It is thought that the reducing research through the analysis on the basic analysis method can not be the core direction of discipline study of science of herbal formula at present. The changes of micro-index can not replace the changes of macro-function and can not be taken as the modernization standard, while real modernization of micro-index and macro-function should be confirm and complement each other. The kernel content of science of herbal formula should be focused on the research of therapies besides the laws of formula design and correlation between formula and syndrome. The research method starts from traditional theory and clinical practice and takes the course of original theory. The science of herbal formula depends on the theoretical innovation for its long-term development, so it is not only a tool in the research of TCM patent medicine.