网格细胞在空间记忆中的作用

The Roles of Grid Cells in Spatial Memory

网格细胞存在于内嗅皮层,具有显著的空间放电特征,并呈现出网格图样的放电结构。近年来网格细胞的发现及其功能研究,为深入阐释空间记忆的神经机制开辟了新的视角。本文详细介绍了网格细胞的发现、神经解剖学联系及空间放电特征;通过网格细胞与位置细胞的对比分析,阐释网格细胞利用自身运动信息进行空间编码的机制,以及在空间记忆中所发挥的路径整合器功能。

Grid cells were found in the medial entorhinal cortex with significant space-discharge characteristics and grid firing fields. Recent studies on grid cells＇ function have brought a new vision for understanding the mechanism of spatial memory. This work basically focused on the discovery, neuroanatomical relationship and discharge characteristics of grid cells. A comparative analysis of place ceils was performed with reference to the spatial encoding mechanism of grid ceils according to the self-motion information and at the same time its role as path integrator in spatial memory was also discussed.