长茎芒毛苣苔化学成分研究

Chemical constituents from Aeschynanthus longicaullis

目的：研究长茎芒毛苣苔Aeschynanthus longicaullis的化学成分。方法：采用各种色谱法分离，运用多种波谱技术鉴定结构。结果：从长茎芒毛苣苔的醋酸乙酯部位分离鉴定了7个化合物：柳杉二醇（1），4（15）-eudesmene—1β，6α—diol（2），2，5-bornanediol（3），异香草酸（4），香草酸（5），豆甾-5，22（E）-二烯-3β-醇（6）和β-谷甾醇（7）。结论：化合物1—5为首次从该科植物中得到，6—7为首次从该植物中分离得到。

Objective： To study the chemical constituents from Aeschynanthus longicaullis. Method： The column chromatographic techniques were applied to isolate the constituents. The spectroscopie methods were used of EI-MS and NMR to identify the structures of the separated compounds. Result： Seven compounds were isolated from the ethyl acetate extract of A. longicaullis, whose structures were elucidated as eryptomeridiol （ 1）, 4 （ 15 ） -eudesmene-1β,6α-diol （2）, 2,5-bornanediol （3）, isovanillic acid （4）, vaniUie acid （5） , stigmast-5 （6） , 22 （23）-diene-3β-ol （6） and β-sitosterol （7）. Conclusion： Compounds 1-5 were isotated for the first time from Gesneriaceae and 6-7 were isolated for the first time from this plant.