妊高症血清尿酸含量的临床分析

Clinical Analysis of Plasma Urine Acid in Pregnancy Induced Hypertension

目的探讨妊娠晚期孕产妇血清尿酸值在妊高症中的变化及其与围产儿预后的关系。方法检测199例妊高症和100例正常妊娠者的血清尿酸、肌酐、尿素氮水平。结果妊高症患者的血清尿酸含量明显高于正常妊娠组（P〈0．01），血清尿酸含量与新生儿低体重儿、窒息、早产呈正相关（p〈0．01），体重负相关（p〈0．05）。结论血尿酸水平与妊高症病情密切相关，可作为围产儿预后的监测指标。

Objective To evaluate the relationship between level of plasma urine acid in pregnancy induced hypertension （PIH） and the outcome of pregnancy.Methods A total of 199 PIH patients and 100 normal pregnant women were entered into this study. The plasma urine acid, creatinine, blood urine nitrogen were tested.Results The level of plasma urine acid in PIH patients was higher than those in normal pregnant women（P〈0.01）. There were positive relationships between plasma urine acid and low body weight, asphyxia and preterm labor（P〈0.01）. There were a negative relationship between plasma urine acid and low body weight, asphyxia and preterm labor（P 〈0.05）. Conclusion It has shown a close relationship between the level of plasma urine acid and the severity of PIH. The level of plasma urine acid could be a clinical marker of fetal outcome.