急性重症胰腺炎并发深静脉血栓形成临床研究

Clinical analysis on deep venous thrombosis complicated by severe acute pancreatitis

目的:探讨急性重症胰腺炎(Severe acute pancreatitis,SAP)深静脉血栓形成(Deep venous thrombosis,DVT)的发病原因、监测方法、治疗及预后。方法:回顾性分析我科13例SAP并发DVT患者的临床资料。结果:SAP并发DVT的主要危险因素为股静脉置管、长期卧床、血液高凝状态。经抬高患肢,抗凝、溶栓治疗7～14d治愈12例,占92.31%(12/13),1例治疗23d后好转,无1例并发肺栓塞及死亡。结论:SAP是DVT的高危致病因素,其中长期留置股静脉置管是主要诱发因素。早发现、早期抗凝溶栓治疗可获得满意效果。

Objective：To investigate the morbidity factors,monitoring ways, therapy and Prognosis of deep venous thrombosis（DVT） complicated by severe acute pancreatitis（SAP）. Methods：A clinical retrospective analysis was carried on 13 cases of DVT complicated by SAP. Results：The major risk factors for DVT complicated by SAP were deep venous catheter in femoral vein（FV）, long-term bed and hypercoagulabale state of blood. 12 patients, about 92.31 percent（12/13）, were cured after the elevation of affected extremity and the treatment with anticoagulation and thrombolysis in 7 to 14 days. One patient was cured after 23 days of these treatments. No patient died of pulmonary embolism. Conclusion：SAP was the high risk etiological factor of DVT. With the effects of factors, deep venous in FV was the major causative factor. Patients with DVT could get satisfactory therapeutic effect by early of finding DVT and early treatment with anticoagulation and thrombolysis.