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慢性鼻窦炎鼻内窥镜手术前后鼻窦粘膜的电镜观察 被引量:8

Electronic microscope observation of sinus mucosa on patients with chronic paranasal sinusitis pre-and post-operation
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摘要 通过对20例慢性鼻窦炎功能性内窥镜鼻窦手术前后的鼻窦粘膜进行了扫描电镜和透射电镜观察。结果发现:术前上皮结构紊乱,细胞表面纤毛断裂、倒伏、脱落,细胞内线粒体减少;鳞状上皮化生,纤维组织增生;杯状细胞增多,上皮下炎性细胞浸润。术后上皮细胞排列整齐,纤毛再生,细胞内线粒体增多,杯状细胞减少。作者认为,慢性鼻窦炎是由于窦口鼻道复合体阻塞,通气引流障碍所引起;功能性内窥镜鼻窦手术能解除阻塞,使窦内氧分压增高,从而使鼻窦粘膜恢复正常形态;组织形态学研究用于鼻窦手术后的疗效评价,不失为一种客观的方法。 The mucosa specimens from twenty patients with chronic sinusitis pre-and post operation taken from the maxillary sinus near the ostia were observed using scan and transmission electron microscope. The results showed that the cillia reduced in number and vacuole discerned between the cilliated columnar cells. The mitochndrins swell and decreased in the ciliated columnar cells, and goblet cells increased in chronic sinusitis. The cilliated columnar cells recovered normal morphoris and function restorated normalization three months after operation. We believe that the chronic paranasal sinusitis was caused by the obstruction of ostiomeatal complex; the functional endoscopic sinus surgery is successful for the chronic paranasal sinusitis. The study of histology and morphology is a new, objective method on evaluation of curative effect for nasal sinus operation. [Chinese Arch Otolaryngol Head Neck Surg, 1998; 5 (4): 210~214 From the Department of Otolaryngology, 163 Hospital of PLA, Changsha 410003 (Dr.Li Zhengxian )1
出处 《耳鼻咽喉(头颈外科)》 1998年第4期210-214,共5页 Chinese Arch Otolaryngology-Head Neck Surg
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