乳腺癌不同手术方式对患者术后生存质量的影响

Influences of different operation modes on the quality of life and quality of marital life of postoperative patients with breast cancer

目的探讨不同手术方式对乳腺癌患者术后生存质量的影响。方法采用已通过检验的美国HopeCity医学研究中心编制的《乳腺癌生存质量评定量表》和Olson婚姻质量问卷,对149例乳腺癌术后1年的患者进行问卷调查分析。结果接受不同手术方式的乳腺癌患者的生存质量(QOL)评分,随手术范围的缩小呈上升趋势。经典根治术与改良根治术、保乳手术方式之间的差异有统计学意义(P<0.05),而改良根治术与保乳手术之间的QOL差异无统计学意义(P>0.05)。乳腺癌患者接受不同方式的手术后,其婚姻质量的评分随手术范围的缩小而呈上升趋势。并且,经典根治术、改良根治术与保乳手术方式之间差异有统计学意义(P<0.05),但仍小于常模。结论接受改良根治术的乳腺癌患者术后生存质量优于接受经典根治术者;保乳手术有助于婚姻质量的提高。

Objective To assess the influence of different operation modes on the quality of life and the quality of marital life in women with breast cancer who have undergone a mastectomy. Methods 149 women aged 〈 60 years one year after mastectomy were included in the study. FACT-B （Functional Assessment of Cancer Therapy＇Breast Quality of Life Instrument） and Olson＇s ENRICH questionnaire were used to assess the quality of life and quality of marital life. Results The study showed that women treated with Halsted radical mastectomy had a lower quality of life than those with modified radical mastectomy and breast conservative surgery （ P 〈 0. 05 ）, and there was no significant difference between modified radical mastectomy and breast conservative surgery （ P 〉 0.05 ）. Quality of marital life was increased with diminution of operation extent （ P 〈 0.05）, but the score of quality of marital life was still lower than that of the norm. Conclusions Patients＇marital life and quality of life can be influenced after mastectomy. Quality of life of the women with modified radical mastectomy is higher than with Halsted radical mastectomy, and breast conservative surgery helps to improve quality of life.