低分子量κ-卡拉胶及其邻苯二甲酰基化衍生物的抗氧化活性研究

Antioxidant Activity of Low-molecular-weight κ-carrageenan and Phthalyl Derivatives of κ-carrageenan

对κ-卡拉胶进行氧化降解,经过透析,得到分子量不同的两种卡拉胶寡糖,并分别制成四丁基铵盐,进而与邻苯二甲酸酐进行酰化,制得两种不同分子量的卡拉胶邻苯二甲酰基化衍生物。对产物进行IR表征,红外光谱表明制得的为目标产物,并检测了产物对超氧阴离子自由基O2-·和DPPH自由基的清除能力。结果表明:κ-卡拉胶在邻苯二甲酰基化以后对上述两种自由基的清除能力均有所增强。

Two kinds of carrageenan-derived oligosaccharides （CDO） with different molecular weight were prepared by oxidative degradation of K-carrageenan and dialysis. Then, these two kinds of CDO were made to two kinds of tetrabutylammonium salts （TBA） respectively, which acylated with phthalic anhydride to obtain two kinds of phthalyl derivatives of K-- carrageenan with different molecular weight. The products were characterized by FI-IR and infrared spectrum indicated that these products were target products. The scavenging activities of products on super oxide anion radical O2-· and DPPH radical were tested. The results showed that the scavenging activities of phthalyl K-carrageenan on super oxide anion radical O2-· and DPPH radical were increased.