妊娠高血压综合征患者血凝四项指标分析

Four blood coagulation indexes analysis in patients with pregnancy induced hypertension syndrome

目的对妊娠高血压综合征患者的凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、凝血酶时间（TT）、血浆纤维蛋白原（FIB）四项检测指标进行分析，探讨妊娠高血压综合征患者的血凝四项指标变化。方法对妊娠高血压综合征患者组（48例）、正常妊娠组（30例）和正常未孕组（30例）患者的血凝四项指标进行分析研究。结果妊娠高血压综合征组与正常未孕组相比，PT、APTT、TT、FIB四项检测结果均显著增高（P〈0．01）；正常妊娠组与正常未孕组相比APTT和FIB均显著增高（P〈0．01），PT和TT均明显增高（P〈0．05）；而妊娠高血压综合征组和正常妊娠组相比，APTT和FIB显著增高（P〈0．01），PT和TT明显增高（P〈0．05）。结论正常晚期妊娠孕妇及妊娠高血压综合征患者均处于高凝状态，而妊娠高血压综合征呈重度高凝状态，检测妊娠妇女血凝四项指标，有利于妊娠高血压综合征的诊断、预防和治疗，对保护母婴健康具有重要意义。

Objective To analysis of PT,APIT,TT and FIB indexes and to explore the changes of hemagglutination indexes in patients with pregnancy induced hypertension syndrome （PIH）. Methods Analysis on PT, APTT, TT and FIB Indexes of 48 cases of patients, 30 cases of pregnant women and 30 cases of healthy controls. Results Four indexes of patients with pregnancy induced hypertension syndrome were higher than that of normal controls （ P 〈 0.05 ）. APTT and FIB indexes of patients were significantly higher than that of the group of pregnant women（ P 〈 0.01 ）. PT and TT indexes of patients were higher than that of the group of pregnant women （ P 〈 0.05 ）. Conclusions The blood coagulation in late pregnancy and patients with pregnancy induced hypertension syndrome both increased,patients with pregnancy induced hypertension syndrome increased significantly. To find out the four indexes in the pregnant women＇s blood - solidifying function is significant for pregnant woman.