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高危型人乳头瘤病毒检测与细胞学检查应用于宫颈癌筛查的比较分析 被引量:4

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摘要 目的探讨高危型人乳头瘤病毒(HPV-DNA)检测与液基薄层细胞学(TCT)应用于宫颈癌筛查方面的比较。方法2008年6月至12月在广西区妇幼保健院随机选取235例接受高危型HPV杂交捕获二代检查(HC2)、230例接受TCT检查,比较两组阳性病例与病理检查结果的阳性符合率。结果HPV-DNA组235例中检出高危型HPV阳性89例,占37.91%,病理检查结果阳性40例,阳性符合率44.94%;TCT组230例中阳性30例,占13.04%,病检结果阳性20例,阳性符合率70.00%。两组阳性率比较P<0.01;两组病检结果阳性符合率比较P<0.05。结论HPV-DNA的阳性检出率明显高于TCT的阳性检出率;但TCT的阳性结果病理符合率高于HPV-DNA的阳性符合率。二者联合应用将大大提高宫颈癌筛查的准确率,降低漏诊率。
作者 梁雯
出处 《中国医药指南》 2009年第22期101-102,共2页 Guide of China Medicine
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