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植物药治疗良性前列腺增生症的研究进展 被引量:2

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摘要 植物药在治疗良性前列腺增生症(BPH)方面已显示出一定的优势和潜力。伯泌松、通尿灵、前列康等在动物和临床试验中均取得了较好的治疗效果。伯泌松(锯叶棕干果提取物)具有抗雌雄激素、抑制5α-还原酶、阻滞肾上腺素受体等可能作用。通尿灵(非洲臀果木提取物)具有抑制与生长因子有关的成纤维细胞的增殖,特别对由碱性成纤维细胞因子导致的成纤维细胞的增殖具有明显的抑制作用。异株荨麻提取物能够抑制前列腺上皮细胞生长;抑制表皮生长因子等作用。前列康(油菜花粉提取物)具有雌激素样作用,可抑制体内5α-还原酶的活性,使双氢睾酮的生成减少。其他的还包括黑麦花粉、灵芝、补骨脂提取物等。近年来,国内外学者用现代科技手段对植物药治疗BPH进行实验和临床研究,为植物药治疗BPH提供了一定的理论及客观依据。但目前大多数植物药的应用仍存在一定的问题,主要是作用机理不明确,起效缓慢,需要在有效性、安全性方面做出更加长期充分的证实。
作者 程芳 陈光亮
出处 《安徽医药》 CAS 2009年第11期1316-1318,共3页 Anhui Medical and Pharmaceutical Journal
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二级参考文献107

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同被引文献23

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