不同年龄段房间隔缺损经皮介入术后右心重构差异

Differences in right cardiac remodeling after percutaneous interventional occlusion for atrial septal defect among different age groups

目的研究不同年龄段房间隔缺损（AsD）经皮介入术后右心形态重构差异。方法回顾性分析经导管介入治疗ASD91例患者的年龄、ASD大小，以及有无发生肺动脉高压（PAH）等资料，并对术前3d及术后3d、3个月、6-12个月做超声心动图随访。结果介入术后ASD患者右心均有恢复，但≥40岁组术后3d至12个月右心大小无进一步的缩小。结论40岁前对ASD纠治右心恢复较好。

Objective To evaluate right cardiac remodeling after transcatheter closure of atrial septal defect （ASD） in different age patients. Methods A retrospective study was conducted of data on the clinical information of the patients （age from 2 to 66 years） who underwent successful transcatheter closure of their ASDs. We performed routine transthoracic echocardiographic studies before closure of the ASD, and 3 days, 3 months, and 6-12 months after closure. Results After ASD close, the enlarged right heart had significantly resumed, but didn＇t continuously decrease further from 3 days to 12 months follow-up in the ≥40 years old group. Conclusion The enlarged right heart can resume better before 40 years old than ≥40 years old.