肝炎患者血浆纤维结合蛋白水平的观察

OBSERVATIONS OF THE LEVEL OF PLASMA FIBRONECTIN OF CASES WITH VIRAL HEPATITIS

103例病毒性肝炎患者血浆Fn测定结果显示,急性肝炎发病期、肝功能恢复正常时血浆Fn升高,慢性肝炎活动期、静止期均在正常水平,而重型肝炎、肝硬化血浆Fn低于正常水平。凝血酶原延长者的血浆Fn显著低于凝血酶原正常者的血浆Fn。提示动态检测血浆Fn似可作判断病情进展及预后的一项参考指标。

The measuring results of plasma fibronectin ( Fn ) of 103 cases of viral hepatitis are reported. It shows that there is a certain increase in the level of plasma Fn during the invasion stage of acute hepatitis and when liver functions become normal. The level of plasma Fn remains normal during the active and resting stages, while that in cases of serious hepatitis and hepatocirrhosis is lower than the normal level. The level of plasma Fn in cases whose prothrombin time is prolonged is lower than in cases whose prothrombin time is normal. It suggests that dynamic inspection of plasma Fn may be an effective basis for judging the advancements and prognosis of diseases.