血清胆汁酸在妊娠期间的变化

Serum Bile Acid Change During Gestational Period

目的监测血清胆汁酸在孕妇妊娠期间的变化。方法对221例不同孕期的孕妇空腹取静脉血,分离血清后检测丙氨酸转氨酶、天冬氨酸转氨酶、总蛋白、清蛋白、总胆红素及胆汁酸等6项指标。结果随着妊娠周数的增加,肝胆汁分泌和排泄受到影响,胆汁酸排泄受阻,导致血清胆汁酸增加。结论胆汁酸是妊娠期非损伤性肝功能改变监测的一个良好指标。

Objective To monitor the serum bile acid change during gestational period.Methods 221 cases of pregnancy women in diverse stage were detected with ALT,AAT,TP,Alb,TB and BA.Results With the weeks of pregnancy increased,the serun BA increased due to liver bile secretion and excretion affection.Conclusion The BA might be a good index to monitor the non-traumatic liver function change.