胆结石手术患者的4种抗菌药物成本-效果分析

Cost-Effectiveness Analysis of 4 Antibacterials in Operative Patients with Gallstones

目的评价4种抗菌药物用药方案预防胆结石手术感染的经济效果。方法运用药物经济学原理,对泰州市人民医院313例胆结石患者使用抗菌药物的4种用药方案进行成本-效果分析。结果头孢尼西钠(罗朗)组(A方案)、头孢匹罗(罗邦)组(B方案)、头孢他定(锋克)组(C方案)、头孢尼西钠(西锐)组(D方案)的成本-效果比分别为10.24,22.07,3.14,18.72,且C方案、D方案均出现不良反应病例。结论A方案为较佳选择。

Objective To evaluate the economic effectiveness of the 4 medication schemes for preventing postoperative infections in the patients with gallstones. Methods The principle of pharmacoeconomics was adopted in the cost- effectiveness analysis of 4 medication schemes. To investigate and study the effect of antibacterial agents used in 313 cases of gallstone in our hospital. Results The cost-effectiveness ratio （CER） for cefonicid （Luolang, scheme A）, cefpirome （Luobang, scheme B）, ceftazidime（Fengke, scheme C）, cefonicid（Xirui, scheme D） were 10. 24, 22.07, 3.14, 18.72 respectively, and the adverse drug reaction （ADR） cases occurred in scheme C and D. Conclusion Scheme A is superior to the others.