摘要
DNA甲基化是基因表达的重要调控方式,是真核细胞中最常见的转录水平的修饰方式之一。DNA甲基化是一种遗传外修饰,在维持细胞正常发育和调节基因表达中起重要作用,异常的甲基化可导致肿瘤的形成,并同癌症发生发展密切相关。
DNA methylation is an important regulation of gene express in eukaryotic cells, and is one of the most common modifications of the transcription level. DNA methylation is an epigenetic modification, and plays an important role of in the cells development and gene expression regulation. An abnormal way of DNA methylation could lead to the formation of tumors and cancers.
出处
《中国实用医药》
2009年第32期218-219,共2页
China Practical Medicine