摘要
目的探讨羊水细胞在染色体疾病产前诊断的应用价值。方法抽取孕中期孕妇羊水,采用羊水细胞原位培养、染色体制备、核型分析。结果3728例标本,培养成功率为99.5%,检出异常核型108例。结论采用羊水细胞原位培养,在产前诊断的应用中获得了满意的结果;有针对性地进行产前诊断,可有效地控制和减少出生缺陷的发生。
Objective：To investigste valuv of amniotic fluid cells in prenatal diagnosis of the chromosome disease.Method：Amniotic fluid cells were cultured from gravidas with prental diagnosis indication,and there karyotypes were analyed by G band.Results：The rate of Training success of 3728 cases is 99.5%,108 abnormal chromosome karyotypes were detected.Conclusions：The success rate of amniotic fluid cells cultured in situ is high.The results are satisfied in the initial application.
出处
《中国优生与遗传杂志》
2009年第11期34-35,共2页
Chinese Journal of Birth Health & Heredity
关键词
养水
细胞培养
染色体疾病
产前诊断
Amniotic fluid
Cell culture
Chromosome disease
Prenatal diagnosis
