口腔外科围手术期患者抗菌药物应用调查分析

Investigation on Perioperative usage of Antimicrobial Agents Analysis Oral Surgery in Patients

目的调查和评价口腔外科围手术期抗菌药物使用情况。方法随机抽取2008年医院口腔外科手术患者365例,对其中预防性应用抗菌药物的品种、联合用药、用药时间、切口愈合进行统计分析。结果口腔外科围手术期患者的抗菌药物总的使用率为100.00%,主要为硝咪唑、氨基糖苷类、头孢菌素类、青霉素类等;其中单用、二联、三联、≥四联用药分别为18.63%(68例)、43.29%(158例)、27.12%(99例)、10.96%(40例);平均用药疗程为8 d。结论应强化医院围手术期预防性应用抗菌药物的合理化意识,以便有效地降低手术期切口的感染率。

OBJECTIVE To analyze the antibiotics usage in perioperative patients of oral surgery in our hospital. METHODS Adopted retrospective review, 365 oral surgery inpatients with operation were investigated on medication, course of treatment, wound healing and so on. RESULTS The utilization 05 antibacterials accounted for 100%. Nitramisole, aminoglycosides,Cephalosporin and penicillins were the main kinds. Single use accounted for 18. 63% （66 cases）, the bigeminy for 43. 29% （158 eases）, the trigeminy for 27. 12% （99 eases）, the utilization with four or more drugs were 18.63% （40 eases）; the average of treatment course was 8 days. CONCLUSIONS To strengthen the management of antibacterials, more education of the principle medicine, usage are helful for reducing surgical site infection.