复合振动仪治疗原发骨质疏松症的短期临床疗效观察

Short period clinical observation of compound vibration machine on the treatment of osteoporosis

目的 初步探讨复合振动仪治疗原发性骨质疏松症的有效性.方法 筛选了70例骨质疏松志愿者,治疗组35例,给予全身复合振动仪治疗,振动强度0.5～0.8 g,频率45～55 Hz,每周3～4次,每次30 min,连续治疗6个月.对照组35例,该组从观察开始到结束,维持原生活规律未作任何治疗.观察两组治疗前后腰椎L2～4BMD 及髋部Neck、大转部Troch、Wardps三角区骨密度变化情况.结果 6个月后,治疗组腰椎L2～4BMD 及髋部Neck、大转部Troch、Wards 三角区骨密度分别平均增长了6.9%、5.9%、5.9%、6.9%;对照组腰椎L2～4BMD 及髋部Neck、大转部Troch、Wards区骨密度分别平均降低了4.7%、4.8%、4.9%、5.1%;两组治疗前后BMD的变化差异均有显著性（P〈0.01）,治疗组和对照组的BMD改变差异均有显著性（P〈0.01）.结论 复合振动仪对原发骨质疏松症患者的骨密度增加有促进作用.

Objective To observe the effect of Compound Vibration Machine on the treatment of Osteoporosis. Methods Seventy volunteers of osteoporosis were selected from a gerocomium and were randomly assigned to a whole body Compound vibration training group （WBCV, n-35） or a control group（CON, n-35）. The intervention of WBCV group consisted of an 6-month whole body compound vibration （30 min/day, 4-5 times per week）. During the 30-minute vibration program, the platform oscillated in an ascending order from 45 to 55 Hz, corresponding to estimated maximum compound accelerations from 0.5 g to 0.8 g. The CON group did not participate in any training,just keeping the normal life as before. Bone mineral density（BMD）was measured at the lumbar 2-4 spine, femoral neck, trochanter, Wards triangle region of hip using DXA at baseline and after the 6- month intervention. Results The BMD in WBCV group after 6-months was showed an increase by 6.9% in lumbar 2-4 spine（L2-4 ）, 5.9% in femur neck,5.9% in trochanter and 6.9% in wards triangle region of the hip, respectively. However, it was decreased by 4.7 % , 4.8 %, 4.9 %, 5.1% correspondingly in CON group. BMD changes in inter-group before and after treatment or between the two groups are significantly different （all P 〈 0.01 ）. Conclusion These findings suggest that the whole body compound vibration training may be a feasible and effective way to raise the BMD of Osteoporosis.