长江流域6城市2005―2007年抗真菌药物应用情况分析

Application of antifungal agents in 6 cities of Yangtze River valley from 2005 to 2007

目的评价长江流域6城市2005―2007年抗真菌药物利用情况。方法收集长江流域6城市157家医院2005―2007年抗真菌药物应用数据,进行金额及用药频度(DDDs)统计分析,对用药金额和DDDs进行排序。结果2005―2007年6城市抗真菌药物用药总金额有所增加,三唑类增幅最大,棘白菌素类增长率最高。金额前2位是氟康唑与伊曲康唑,DDDs前2位是伊曲康唑与特比萘芬;进口药及合资药占据70%以上市场,国产药比例逐年下降。结论2005―2007年长江流域6城市抗真菌药物用药金额呈增长趋势,三唑类增长最明显。

AIM To investigate the application of antifungal agents in 6 cities of Yangtze River lrom 2005 to 2007. METHODS Application of antifungal agents in 157 hospitals of 6 cities from 2005 - 2007 were analyzed according to the orders of sum and DDDs in the databases of each city. RESULTS The total cost of antifungal agents used in 6 cities increased with an annual growth rate of 29.23% from 2005 to 2007. Chongqing ranked high in 6 cities with an annual growth rate of 38.53%. The sum of triazole was the highest. The increase rate of echinocandina, a new type of antifungal agent, was the largest. Fluconazol and itraconazole were in the top of sum. Itraconazole and terbinafine were in the top of DDDs. Over 70% were imported and joint venture products and the domestic drugs decreased year by year. CONCLUSION The sum of antifungal agents, especially the triazole, appears increasing trend in 6 cities of Yangtze River valley.