中医主症程度的量化赋分值与证候疗效评价的相关性分析

Correlative analysis of assessment score of main symptom and efficacy evaluation of traditional Chinese medicine syndrome

目的探索中医证候疗效评价时症状分级量化方法设计合理性的评价方法。方法基于既往研究的83个数据库[病例数(282±s125)例,症状总数(8.0±2.0)个,主症数量(3.0±1.0)个],分析主症权重为1、2、3的3种赋分方案间中医证候疗效和主症改善一致率的差异,以及不同症状总数及主症数量的赋分方案间主症改善一致率趋势的一致性,以主症改善一致率高低评价主症赋分方案的合理性。结果主症权重为1、2、3的3种赋分方案主症改善一致率分别为(82±11)%、(87±10)%、(90±8)%,差异显著(P<0.01),症状总数和主症数量与赋分方案间主症改善一致率均无交互作用(P>0.05)。结论3种赋分方案中,方案3的主症改善一致率最高,其中医证候疗效评价结果较为合理。

AIM To explore a reasonable assessment method for quantization of main symptom in efficacy evaluation of traditional Chinese medicine （TCM） syndrome. METHODS Based on the 83 databases of previous research （patients （285±s 125）, symptoms （8±2）, main symptoms （3± 1））, the difference of traditional Chinese medicine syndromes （TCMS） and main symptoms amelioration concordance rate （MSACR）, the consistency of MSACR, and the rationality of the plan was analyzed in 3 score pian, in which the weight of main symptoms was 1, 2, 3, respectively. RESULTS The MSACRs of 3 score plan were （82± 11）%, （87 ± 10）%, （90 ± 8）%, respectively. There were significant differences between 3 score plan （P 〈 0.01）. There were no interactions of the MSACRs among the score plan, syptom number, and main symptom number （P 〉 0.05）. CONCLUSION The MSACR and TCMS of the third plan is the best in 3 score plan, and it＇s result of efficacy evaluation of TCM is reasonable.