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脂联素与慢性肾功能不全 被引量:1

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摘要 脂联素是脂肪细胞分泌的一种生物活性分子,是一种蛋白质激素,具有抗炎、抗动脉粥样硬化的作用。炎症、氧化应激与内皮功能紊乱一起加速了终末期肾脏病患者动脉粥样硬化的发生,尽管终末期肾脏病血液透析、腹膜透析患者和中度肾功能不全患者高发胰岛素抵抗和心血管疾病,但血脂联素水平增加。低脂联素与心血管疾病预后差有关,血脂联素可能减轻血液透析患者氧化应激。本文对脂联素与慢性肾功能不全的关系作一综述。
作者 王东红
出处 《国外医学(老年医学分册)》 2009年第6期269-272,共4页 Foreign Medical Sciences(Geriatrics)
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同被引文献7

  • 1冯利平,张玲,钟玲,朱冬菊,刘玲.维生素E对维持性血液透析患者氧化应激及微炎症状态的影响[J].中国实用内科杂志,2007,27(3):215-217. 被引量:16
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  • 6Ciocouu M, Badescu M, Paduraru I. Protecting antioxiclative effects of vitamins E and C in experimental physical stress[J]. J Physiol Biochem , 2007 ,63 (3) :1872-1941.
  • 7梁敏,侯凡凡,田建伟,刘俊,张国华,林跃萍,魏冬梅,陈瑗.终末期肾病氧化应激状态的研究[J].解放军医学杂志,2003,28(6):540-541. 被引量:15

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