摘要
目的:探讨了血清CEA、NSE、CA19-9和VEGF水平在肺癌患者中的变化。方法:分别应用放射免疫分析和ELISA对31例肺癌患者进行了血清CEA、NSE、CA19-9和VEGF测定,并与35名正常健康人作比较。结果:肺癌患者血清CEA、NSE、CA19-9和VEGF水平均非常显著地高于正常人组(P<0.01),且CEA、NSE、CA19-9和VEGF呈明显正相关(r=0.6218、0.6101、0.6317,P<0.01)。结论:检测肺癌患者血清CEA、NSE、CA19-9和VEGF水平的变化对了解病情、指导临床实践均具有重要的临床价值。
Objective To explore the clinical significance of changes of serum CEA,NSE,CA19-9 and VEGF levels in patients with lung cancer.Methods Serum CEA,NES,CA19-9（with RIA）and VEGF（with ELISA） levels were detected in 31 patients with lung cancer and 35 controls.Results The levels of serum CEA,NSE,CA19-9 and VEGF were significantly higher in the patients than those in controls（P〈0.01）.Serum CEA,NSE,CA19-9 levels were positively correlated with the VEGF levels（r=0.6218,0.6101,0.6317,P〈0.01）.Conclusion Serum CEA,NSE,CA19-9 and VEGF levels were closely related to the diseases process of lung cancer and were of prognostic values.
出处
《放射免疫学杂志》
CAS
2009年第4期332-334,共3页
Journal of Radioimmanology
关键词
肺癌
癌胚抗原
神经元特异性烯醇化酶
糖类抗原-19-9
血管内皮生长因子
lung cancer carcinoembryonic antigen（CEA） neuron-specific enolase（NSE） carbohydrate antigen 19-9（CA19-9） vascular endothelial growth factor（VEGF）
