期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

前哨淋巴结微转移在结直肠癌预后与治疗中的意义 被引量：2

下载PDF
导出
摘要 结直肠癌（CRC）是常见的恶性肿瘤，淋巴结转移是除远处转移外最重要的预后因素，有淋巴结转移的Ⅲ期患者约30％在根治术后5年内复发，而常规病理检查无淋巴结转移的Ⅰ、Ⅱ期患者也有约5％～35％的机会仍会复发和／或转移，可能是这些患者有未被检出的“残留”肿瘤微转移或肿瘤具有侵袭性的生物学行为。常规病理检查对CRC淋巴结有无转移的判断存在缺陷。
作者 左明 庄文
机构地区 四川省肿瘤医院腹部外科 四川大学华西医院
出处 《肿瘤预防与治疗》 2009年第4期457-460,438,共5页 Journal of Cancer Control And Treatment
基金 四川重点科技自筹项目(05JY029-164)
关键词 结直肠癌 前哨淋巴结 微转移
分类号 R735.3 [医药卫生—肿瘤] R730.6 [医药卫生—肿瘤]
  • 相关文献

参考文献36

  • 1Letitia BH, Jessica B, Clifford YK. Colorectal cancer: epidemiology and health services research[ J]. Surg Oncol Clin N Am, 2006,15 (1) :21-37.
  • 2Green FL, Stewart AK, Norton HJ. New tumor node metastasis staging stratetegy for node positive ( stageIII) rectal cancer:an analysis [J]. J Clin Oncol,2004,22:1778-1784.
  • 3Park YJ, Park KJ, Park J-G, et al. Prognostic factors in 2230 Korean colorectal cancer patients : Anaalysis of consecutively operated cases[J]. World J Surg,1999,23(2) :721-726.
  • 4Lee MR, Hong CW, Yoon SN, et al. Isolated tumor cells in lymph nodes are not a prognositic marder for patients with stage I and stage II eolorectal cancer [ J ]. J Surg Oncol,2006,93 : 13-19.
  • 5Krag DN, weaver DL. Pathological and molecular, assessment of sentinel lymph nodes in solid tomors[ J]. Semin Oncol,2002,29 (3) :274-279.
  • 6Wood TF, Nora DT, Morton DL, et al. One hundred consecutive cases of sentinel lymph node mapping in early colorectal carcinoma:detection of missed micro metastases [ J ]. J Gastreen Surg , 2002,6(3 ) :322-329.
  • 7Clarke G, Ryan E, O, Keane JC, et al. The detection of cytokeratins in lymph nodes of Dukes B colorectal cancer subjects predicts a poor outcome [ J ]. Eur J Gastroenterol Hepatol, 2000,12 ( 5 ) : 549-552.
  • 8袁宏银,程伏林,魏正专,杨国樑,陈家宽.逆转录聚合酶链反应检测结直肠癌淋巴结微转移的临床意义[J].癌症,2004,23(9):1069-1073. 被引量：16
  • 9邹忠武,杨传永.A、B期直肠癌淋巴结微转移的研究[J].临床外科杂志,2004,12(12):735-737. 被引量：1
  • 10Amelda QC, Lopes A, Araujo I, et al. Retroperitoneat and lateral pelvic lymphadenectomy mapped bylymphoscintigraphy and blue dye for rectal adenocarcinoma staging:preliminary results[ J]. Ann Surg Oncol,2006,13 (12) : 1617-1621.

二级参考文献48

  • 1Hayashi N,Ito I,Yanagisawa A,et al.Genetic diagnosis of lymph node metastases in colorectal cancer [J]. Lancet,1995,345(7):1257- 1262.
  • 2Greenson JK,Isenhart CE,Rice R,et al. Identification of occult micrometastases in pericolic lymph node of Dukes B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49: correlation with long term survival [J]. Cancer,1994,73:563- 569.
  • 3Futamura M,Takagi Y,Koumura H,et al. Spread of colorectal cancer micrometastases in regional lymph node by reserse transcriptase polymerase chain reactions for carcinoembryonic antigen and cytokeratin 20 [J]. J Surg Oncol,1998,68:31- 40.
  • 4Gusterson B.Are micrometastases clinically relevant? [J]. Br J Hos Med,1991,47:247- 248.
  • 5Raj GV, Moreno JG, Gomella LG. Utilization of polymerase chain reaction technology in the detection of solid tumors [J]. Cancer, 1998, 82:1419- 1423.
  • 6Dorudi S, Kinrade E, Marshall NC, et al. Genetic detection of lymph node micrometastases in patients with colorectal cancer [J]. Br J Surg, 1998, 85:98- 100.
  • 7Bustin SA,Gyselman VG,Williams NS,et al.Detecection of cytokeratins19/20 and guanylyl cyclase C in peripheral blood of coloreactal cancer patients [J]. Brit J Cancer, 1999, 79(5)1813- 1819.
  • 8Dobashi K, Sugio K, Osaki, et al. Micrometastatic p53 positive cells lung cancer: prognostic significance [J]. J Thorac Cardiovasc Surg, 1997, 114:339- 345.
  • 9Greenson JK,Isenhart CE,Rice R,et al.Identification of occult micrometastases in pericolic lymph nodes of Dukes'B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49.Correlation with long-term sarvival.[J]Cancer,1994,73(3):
  • 10Moll R,Schiller DL,Franke WW,et al.Identification of protein IT of the intestinal cytoskeleton as a movel type I cytokeratin with unusual properties and expression patterns[J].J Cell Biol,1990,111(2):567-580.

共引文献23

同被引文献24

  • 1季政一,陈德建,戴雪明,裘正军.Dukes B期结直肠癌淋巴结微转移对预后的影响[J].上海医学,2006,29(7):423-425. 被引量：2
  • 2陈路,崔喆,钟鸣,陈锦先,王少华,王平治.癌旁淋巴结微转移对结肠直肠癌复发和转移的意义[J].外科理论与实践,2007,12(5):496-497. 被引量：3
  • 3Siegel R,Naishadham D.Jemal A,et al. Cancer statis-tics,2012[J]. CA Cancer J Clin,2012,62( 1): 10-29.
  • 4Enker WE,Havenge K,Polyak 丁,et al. Abdominoper-ineal resection via total mesorectal excision and auto-nomic nerve preservation for low rectal cancer [J]. ,World J Surg,1997,21:715-720.
  • 5Chor PW,Yu CS,Jang SJ ,et al. Risk factors for lymphnode metastasis in submucosal invasive colorectalcancer[J]. , World J Surg,2008,32(9) :2089.
  • 6Derwinger K,Kodeda K,Bexe-Lindskog E,et al.Tumour differentiation grade is associated with TNMstaging and the risk of node metavstasis in colorectal incancer[J]. Acta Oncologica,2010,49(1) : 57-62.
  • 7Saha S. Nora D, Weise D, et al. Sentinel lymph nodemapping in colorectal cancer—a review [J]. Surg ClinNorth Am,2000,80(6) :181M819.
  • 8Kitagawa Y, Fujii H, Mukai M, et al. The role of thesentinel lymph node in gastrointestinal cancer[J]. SurgClin North America,2000 ,80(6) : 1799-1801.
  • 9Guo X,Wang C,et al. Occult tumor metastasis and theprognostic value of sentinel lymph nodes in rectalcancer[J]. Oncol Lett,2012,3(2) :411-414.
  • 10Van der Zaag ES,Kooij N.Vail de Vijver MJ,et al. Di-agnosing occult tumour cells and their predictive valuein sentinel nodes of histologically negative patientswith colorectal cancer[J]. Eur J surg Oncol, 2010, 36(4).350-357.

引证文献2

二级引证文献3

肿瘤预防与治疗
2009年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部