上海地区215例成人麻疹患者的临床分析

Clinical Analysis of 215 Adult Measles Patients in Shanghai

目的分析成人麻疹患者的流行病学及临床特征,总结成人麻疹的特点。方法回顾性分析近3年上海市第5人民医院收治的215例成人麻疹患者的流行病学及临床资料。结果①麻疹发病年龄主要在18～35岁之间。②未接种过麻疹疫苗的患者有67.9%。③主要并发症有肝功能异常[183例(85.1%)],结膜炎[82例(38.1%)],腹泻[49例(22.8%)],肺部感染[41例(19.1%)]等。结论成人麻疹的并发症以肝功能异常最多见。成人麻疹发病率高与未进行麻疹疫苗接种、麻疹疫苗接种时间太长、抗体滴度降低及流动人群发病率高有关。

[ Objective] To analyze the epidemiological and clinical characteristics of adult measles patients, summarize the charac- teristics of adult measles. [Methods]The epidemiological and clinical data of 215 adult measles patients in Shanghai 5th people hospital in recent 3 years were analyzed retrospectively. [Results] （1） The age of patients mainly was at 18 - 35 years old. （2） 67.9% patients haven＇t been vaccinated. 13） The main complications were hepatitis （183cases, 85.1% ）, conjunctivitis （82 cases, 38.1% ）, diarrhea （49 cases 22.8% ）, pneumonia （41cases, 19.1% ）, etc. [ Conclusion] The most common complication of adult measles patients is abnormal liver function. The reason of the high morbidity of adult measles included vaccination absence, a long time after vaccination, low antibody concentration low and high morbidity in floating population.