2004—2007年十堰市健康人群流行性脑脊髓膜炎带菌情况

Carrying Status of Epidemic Cerebrospinal Meningitis among Healthy Population in Shiyan City during 2004—2007

目的了解十堰市健康人群流行性脑脊髓膜炎(流脑)带菌状况及菌群分布,为合理制定有效的预防措施提供依据。方法于每年流行前期(10—12月份),随机采集健康人群咽拭子,接种卵黄双抗琼脂平板分离培养,并挑取疑似菌落进行染色镜检、生化鉴定及血清分型。结果2004—2007年健康人群流脑总带菌率为2.90%(35/1206),以B群为主,B群带菌率为1.57%(19/1206),各年龄组人群流脑带菌差异有统计学意义(P<0.01),性别无显著差异(P>0.05)。结论十堰市健康人群带菌率较低,带菌菌群以B群为主,A群次之。高中生和福利院老人健康带菌率较高,应作为流脑重点防控人群,加强流脑疫苗预防接种和病源学监测。

[ Objective ] To understand the carrying status of epidemic cerebrospinal meningitis among healthy population and the flora distribution, and provide evidence for rationally developing effective control measures. [ Methods] Throat swabs were colleted from healthy people before epidemic period { October--- December）, and inoculated on EPV plate, then suspected colony was picked, stained, biochemical identified and serological typed. [ Results ] The epidemic cerebrospinal meningitis carrying rate among healthy people was 2.90% （35/1206} during 2004n2007, B serotype as major with carrier rate of 1.57% （19/1206） ; the difference of carrier rate was significant （ P 〈0.01 ） among various age groups, but negligible between genders（ P 〉0.05）. [ Conclusion] The carrier rate among healthy people is low, B serotype as major, followed by A serotype; students in high school and elder persons in welfare house who have a high carrier rate should be taken as a focus population for epidemic cerebrospinal meningitis control, vaccination and pathogenic surveillance should be strengthened on them.