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靶向放射增敏作用机制的研究进展

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摘要 随着生命科学研究的深入,靶向增敏药物的研发主要以一些与肿瘤细胞分化、增殖相关的细胞信号转导通路的关键酶作为药物筛选靶点,发掘出选择性作用于特定单个或多个靶点的高效、低毒、特异性强的新型抗癌药物。恶性肿瘤细胞内的信号转导、细胞周期的调整、细胞凋亡的诱导、细胞与胞外基质的相互作用等各种基本过程正在被逐步探知并阐明。近年来,靶向性增敏药物的研究与开发取得了长足的进展,随着基础和临床研究的深入,发现分子靶向药物、细胞毒性药物与射线有明显的协同作用,
出处 《中华放射医学与防护杂志》 CAS CSCD 北大核心 2009年第5期554-556,共3页 Chinese Journal of Radiological Medicine and Protection
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