核素肾动态显像对宫颈癌患者肾功能及形态检测的评估

Clinical application of ^(99m)Tc-DTPA dynamic renal scan in the treatment of cervical cancer

目的探讨^(99m)锝-喷替酸(^(99m)Tc-DTPA)肾动态显像在宫颈癌患者肾功能及形态检测中的应用价值。方法对确诊宫颈癌患者230例分别行双肾B型超声、血肌酐、^(99m)Tc-DTPA肾动态显像。通过对三种检查结果的比较,评价^(99m)Tc-DTPA肾动态显像在宫颈癌患者肾功能及形态检测中的应用价值。结果所有患者的血清肌酐均正常,未检出肾功能异常。双肾B超检出肾积水24例、肾囊肿10例、肾结石5例、单侧肾小20例、双侧肾小8例。^(99m)Tc-DTPA肾动态显像检出单侧或双侧肾小球滤过率(GFR)下降共74例,单侧或双侧肾积水共42例,单侧或双侧肾盏肾盂排泄欠通畅115例,肾囊肿3例,单侧或双侧。肾小28例,双侧肾大11例。结论 ^(99m)Tc-DTPA肾动态显像能更精确的评价肾功能,同时能了解肾的形态学变化。在宫颈癌的治疗中,^(99m)Tc-DTPA肾动态显像是一项能较全面评价肾脏情况的检查方法。

Objective： To evaluate the value of clinical practice of ^99mTc-DTPA dynamic renal scan in the treatment of cervical cancer. Methods： Two hundred and thirty patients were included. All patients had blood test of serum creatinine, renal ultrasonograhpy, ^99mTc-DTPA dynamic renal scan in one week. The data were analyzed to evaluate the value of ^99mTc-DTPA dynamic renal scan in the treatment of cervical cancer. Results： The results of serum creatinine of all patients were in the normal range. Twenty-four cases of hydronephrosis, 10 of renal cyst, 5 of renal calculus, 20 of unilateral renal atrophy, and 8 of bilateral renal atrophy were detected with the renal ultrasonography. Seventy-four cases of unilateral or bilateral renal GFR decline, 42 of unilateral or bilateral hydronephrosis, 115 of slightly abnormal stasis of urine in unilateral or bilateral renal pelvis, 3 of renal cyst, 28 of unilateral or bilateral renal atrophy, and 11 of bilateral renal hypertrophy were detected with ^99mTc-DTPA dynamic renal scan. Conclusions： ^99mTe DTPA dynamic renal scan can provide accuracy GFR and information about morphological changes of renal. Consequently, during the treatment of .cervical cancer,^ 99mTc-DTPA dynamic renal scan is a examination method for comprehensive evaluation of renal.