住院抑郁症患者生命质量与疾病影响程度调查

Investigations on Quality of Life and the Sickness Impact of the Depressive Patients

目的：了解抑郁症患者的生命质量与疾病影响程度,探讨抑郁程度、生命质量和疾病影响程度的关系。方法：运用随意抽样方法,对2007年7-9月在四川大学华西医院心理卫生中心住院的抑郁症患者进行问卷调查。问卷包括：①一般人口学资料;②Zung抑郁自评问卷SDS;③汤旦林生命质量表TD;④美国华盛顿大学卫生服务系1977年编制、我国李君荣、张新平等翻译的疾病影响程度量表SIP。统计方法：采用SPSS10.0软件对数据进行处理,采用频数分析t、检验、相关分析和ANOVA多元线形回归分析。结果：①住院抑郁症患者TDL为60.04＋16.95,男女患者无显著性差异（T1=-0.726 sig=0.47）;②多数抑郁症患者的TDL处于比较差和中下水平（比较差占62.7%,中下占17.9%;③患者受疾病影响严重,SIP总平均受损分为40.01＋15.74,其中社会心理功能影响平均分为53.86＋22.22,其他功能影响平均分为45.09＋17.81,躯体功能影响平均分为21..84＋14.85;④抑郁症患者TDL、SIP和SDS有一定关系,分别SDS与TDL的相关系数r=0.248,sig为0.043,SDS与SIP的相关系数r=0.526,sig为0.000;⑤患者的TDL与性别、病程、住院次数、职业、付费方式无显著性相关关系,而与年龄有一定关系（R=-0.255,Sjg=0.037）;⑥患者的SIP与患者的与年龄、病程、住院次数、付费方式、职业等无显著性关系,P〉0.05。而与性别有一定关系,R=0.249,Sjg=0.042。结论：①抑郁症患者的生命质量TDL严重下降,明显低于正常人,而且处于比较差和中下的患者占多数（差为69.6%,中下为17.9%）;②抑郁症患者疾病影响严重,SIP功能损失分为40.01＋15.74,其中社会心理影响最严重,为53.86＋22.22;③抑郁症患者的SDS与TDL和SIP有明显相关性;④抑郁症患者的TDL与年龄有一定关系,SIP与性别有一定关系。

Objective：To investigate the quality of life and the sickness impacts of depressive patients,analyzing the relationship among the depressive degree,sickness impact and the quality of life.Methods：The depressive patients hospitalized in the Mental Health Center of West China Hospital,from July to september in 2007 were investigated.Four questionaries were used in the investigation：①The general material scale.②Zung Self-Rating Depression Scale（SDS）.③The Sacle of Quality of Life designed by Tang Dan-lin（TDL）.④The Sickness Impact Profile（SIP）,compiled by The Health Service of Washington University in 1977 and translated by Li Jun-rong,Zhang Xin-ping.The statistics methods adopted were：the Frequency Analysis,the T Test,the Relevent Analysis and the Llinear Regression Analysis.Results：1.The average scores of the life quality of the patient was 61.20±15.48,in which male was 67.78±15.85,the female was 56.11±13.83.There are remarkable differences of life quality between male and female patients,that is,the life quality of the male is higher than that of the female（T1=3.118 sig=0.003）.2.The life quality of most depressive patients were relatively bad,in which the TDL lower than 65 points accounted for 61.2%,TDL under medium level（65-74 points） accounted for 16.4%,TDL at the medium condition（75-89 points） accounted for 20.9%,the TDL in quite good level（〉90 points）only accounted for 1.5%.3.The items of TDL in the low points were：T1,T6,T8,T9,T10,T11,T12,T14,T15,T16 and the items in the lowest points were：T9,T10.4.The life quality of patients had remarkably minus relationship with the depressive degree,sickness impact degree,the course of the disease and the number of hospitalization（P〈0.001）,had remarkable relationship with the age and the sex（P〈0.001）,but had noting to do with the occupation and the way of payment（P〉0.05）.5.The life quality of depressive patients influenced by the serious degree of the disease..The average point of SIP was 40.01±15.74,and the point of social psychology was 53.86±22.22.Other functional influence ponit was 45.09±17.81.The the point of body function was 21.84±14.85.6.The sickness impact degree of patients had remarkably relationship with the quality of life and the depressive degree（P〈0.001）,but had no relationship with with the age,the sex,the number of hospitalization,the occupation and the way of payment（P〉0.05）.Conclusion：1.The life quality of depressive patients decreased remarkably and was lower than healthy people.Most of their life quality was under medium or even lower conditions.2.The degree of depression had influences on the patiens＇ life quality and the social psychology aspect was affected seriously.3.The life quality of patients had remarkable relationship with the depressive degree,sickness impact degree and had relationship with the age,the sex,the course of the disease and the number of hospitalization,but has nothing to do with the occupation and the way of payment.